Yes. Beyond the athletic advantages provided by GPS Circulate, there are additional physiological effects that are often noted from its use. These can arise from vascular effects of the nutrient composition, (those resulting in the more efficient delivery of nutrients/oxygen throughout the body), as well as from the support of HGH (human growth hormone) release from the pituitary and from supported production of the neurotransmitter GABA (gamma aminobutyric acid). The key ingredients in GPS Circulate are L-arginine and L-citruline amino acids that work by increasing nitric oxide levels in the body and improving the elasticity of the arteries thus facilitating blood flow. These physiological effects can include quicker recovery, improved mood/anxiety levels, increased muscle mass and heightened sexual function in men and women.